It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil drug reviews Plaquenil muscle pain Plaquenil cost walgreens Is extreme fatigue a side effect of Plaquenil - NRAS. Is extreme fatigue a side effect of Plaquenil. I've been on Plaquenil now for three months and its starting to help with the pain although I have diarrhoea every day but it's manageable. But I'm really struggling with fatigue now - worse than its ever been. You didn't mention if you were taking hydroxychloroquine generic for Plaquenil. My Rhumy prescribed it along with Tramadol pain Med and it took a few months but most of my pain seems to have subsided. And I don't have any problems sleeping. I don't take any kind of sleeping pill, but do sweat and get chills sometimes but no pain. I've been on plaquenil since 2011 and I haven't had any issues like that with it. Not even any unusual dreams. I do get sleep paralysis on very rare occasions, but that started well before the plaquenil, and I've only had one incident since. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Does plaquenil help with sleep Plaquenil & Weight Gain/Loss -, Difficulty Sleeping - New Member Checkin - Sjogren's. What does hydroxychloroquine sulphate do The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Foods to Avoid When Taking Plaquenil Oral. Hydroxychloroquine/plaquenil and sleepwalking lupus. What Conditions does Plaquenil Treat? - WebMD. Plaquenil gave me anxiety and I could not sleep while taking a higher dose. You should probably call your doctor and tell them. Maybe they can adjust your milligrams to a lower dose to see if that is what is causing the insomnia. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Insomnia because of plaquenil. Been off of plaquenil for about 5 months and I can tell difference of my sleep. I sleep more hours during those periods I stop taking plaquenil. Now, that I am back taking plaquenil I could hardly sleep. I think I just sleep 2 hours or less or a little bit more than 2 hours each night.