Most types of panniculitis have both septal inflammation (early) and lobular inflammation (later). Further classification is based on whether or not there is subcutaneous The outcome depends on the underlying cause of the inflammation. How long for hydroxychloroquine to leave the body Chloroquine p53 lysosome RESULTS The study included 300 patients with discoid lupus erythematosus n = 160, subacute CLE n = 86, lupus erythematosus tumidus n = 52, chilblain lupus n = 26, and lupus panniculitis n = 16; 38 of these patients had 2 or more associated forms. Quinine was first recognized as a potent antimalarial agent hundreds of years ago. Since then, the beneficial effects of quinine and its more advanced synthetic forms, chloroquine and hydroxychloroquine, have been increasingly recognized in a myriad of other diseases in addition to malaria. Patients with lupus panniculitis overlap features can be tried on oral hydroxychloroquine. Given the cytotoxic phenotype of SPTCL, interferons should be avoided. Lesions on the distal legs will take longer to resolve than proximal lesions. Just recently diagnosed after about a year going to see different doctors. We have only had a few members come thru with Lupus Panniculitis (Profundus), and I don't believe any of them have posted in the last few months. After an inflammatory phase of weeks to months, panniculitis often settles down. Some forms of panniculitis do not leave a mark, but destructive forms of panniculitis tend to leave a permanent dent in the skin. Hydroxychloroquine lupus panniculitis Lupus and Panniculitis - Treato, Hydroxychloroquine From Malaria to Autoimmunity SpringerLink Increase in malaria deaths after chloroquine failure Generalized lupus panniculitis has been described in patients with C2 or C4 deficiency 24 and in patients with antiphospholipid syndrome 25. Lesions may be painful. The overlying skin can be normal or show erythema, atrophy, or ulceration 26. Lesions heal with atrophy and scarring. Lupus Erythematosus Panniculitis - an overview.. Subcutaneous panniculitic T cell lymphoma subcutaneous.. Case report on a patient with lupus panniculitis. Lupus panniculitis is an unusual variant of lupus erythematosus. Most of the patients are adults in the age group of 20-60 years. Persistent, firm, well defined nodules and plaques on face, scalp, breast, arms, thighs, and buttocks characterize it generally, which may ulcerate and heal with scarring. Ulceration is rarely seen. Lipoatrophic panniculitis is generally considered to be a rare disease affecting children. We report a case involving this condition in an adult patient presenting with striking clinical features. Subcutaneous panniculitis-like T-cell lymphoma. Clinical presentation with dull erythematous lesions and lipoatrophy. Credit JAAD In a histologic review of 19 cases of LEP, Park et al found that most specimens revealed lymphoplasmacytic lobular panniculitis with epidermal and dermal changes of lupus, hyaline fat necrosis, and lymphoid follicles.