Suicidal chloroquine poisoning

Discussion in 'Canadian Online Pharmacies' started by anyloalpesy, 03-Mar-2020.

  1. Alexei.Popov XenForo Moderator

    Suicidal chloroquine poisoning


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    My question for a person asking if it is safe to take chloroquine would be, how badly were you floxed? As we know FQ’s exhibit cumulative toxicity. From the article I referenced above we know that Chloroquine is a chemical cousin to the FQ’s so it is entirely plausible that Chloroquine would contribute to the cumulative toxicity. Chloroquine poisoning, on the other hand, is well understood due to its widespread use in parts of Asia, Africa and Europe for inducing abortion and attempting suicide.6 9 Animal studies have shown the toxicity profile of chloroquine to be approximately two to three times that of hydroxychloroquine.7 Moreover, fatality rates for chloroquine. The only study in humans looking at severe chloroquine overdoses was done by Riou et al in 1988. 12 The criteria for severe chloroquine poisoning was an ingestion of 5 grams, which a retrospective study had determined to be an accurate predictor of a fatal outcome. They treated 11 prospective chloroquine overdose patients with immediate.

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    Suicidal chloroquine poisoning

    PDF Fatal suicidal poisoning by Chloroquine in presence of., Accidental hydroxychloroquine overdose resulting in.

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  6. Chloroquine is an aminoquinoline used for the prevention and therapy of malaria. It is also effective in extraintestinal amebiasis and as an antiinflammatory agent for therapy of rheumatoid arthritis and lupus erythematosus. Chloroquine is not associated with serum enzyme elevations and is an extremely rare cause of clinically apparent acute liver injury.

    • Chloroquine - LiverTox - NCBI Bookshelf.
    • Treatment of hydroxychloroquine overdose - ScienceDirect.
    • Grand Rounds-Hammersmith Hospital.

    Arch Toxikol. 1968;233204-8. Fatal, suicidal chloroquine poisonings. Ifftsits-Simon C. PMID 5704788 PubMed - indexed for MEDLINE MeSH Terms Abstract No therapy has been proved to be effective for patients with severe chloroquine poisoning, which is usually fatal. In a retrospective study of 51 cases, we found that ingestion of more tha. Suicidal overdose of chloroquine is rare. We present a 14-year-old girl who was admitted to our Emergency Department after intentional ingestion of 7.5 g of chloroquine base followed by cardiac and respiratory arrest. Despite early mechanical ventilation, cardiac support, and treatment with high doses of diazepam, the patient died.

     
  7. maxskvo New Member

    Background: The American Academy of Ophthalmology recommendations on screening for chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Treatment of severe chloroquine poisoning. Chloroquine poisoning • LITFL • Clinical Case Tox Conundrum Hydroxychloroquine-Induced Retinal Toxicity - American.
     
  8. ProFSM Well-Known Member

    Hydroxychloroquine is in a class of drugs called antimalarials. Plaquenil hydroxychloroquine - Netdoctor Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses RA and Hydroxychloroquine How Effective is it for Rheumatoid.
     
  9. GipperAlex Guest

    Reversal of Chloroquine Resistance Malaria in Malawi In 1993, when the clinical efficacy of chloroquine CQ against falciparum malaria dropped below 50%, Malawi replaced this agent countrywide with sulfadoxine-pyrimethamine SP for first-line treatment of uncomplicated malaria.

    History of antimalarials Medicines for Malaria Venture
     
  10. gerby Guest

    Hydroxychloroquine for children and young people - JIA Hydroxychloroquine must be stopped during the weeks or months of breast feeding as it is transferred in breast milk. Hydroxychloroquine and Alcohol. As hydroxychloroquine is nearly always prescribed alongside other DMARDs it is really important that any advice that relates to another DMARD must be acknowledged and used as the guide for this drug.

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