Suddenly I'm experiencing eye problems (blilnd spots). I have stopped taking plaquenil, but now I'm being told by doctors that the damage is not necessarily reversible especially if you have taken it for a long time. Plaquenil dosage for ra Hydroxychloroquine sulphate tablets in india Chloroquine autophagy protocol The investigators think that there is a connection between the use of plaquenil and the prevention of Age related macular degeneration AMD. The investigators believe that the use of plaquenil makes bruch's membrane thicker, thereby preventing Chroidal Neovascularization CNV growth. The macular degeneration association, inc. is a registered 501c3 non-profit corporation. a copy of the official registration and financial information may be obtained from the division of consumer services by calling toll-free within the state 1-800-help-fla or on the consumer services website registration does not imply endorsement, approval, or recommendation by the state. Aug 30, 2011 Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. It is now considered for new disease. My mother was diagnosed with Plaquenil Toxicity in 2007 she first noticed changes in 2006, although being followed by her eye doctor they failed to notice this as Plaquenil TX until it was to late. I'm hoping to find people who have recovered from the eye damage. Plaquenil macular degeneration Multimodal Imaging in Plaquenil Toxicity, Plaquenil Macular Degeneration Association Does plaquenil affect healing after bone surgery The other day when I was at the opthamologist, for my visual field test for plaquenil, the assistant said I needed to be dilated because "having macular degeneration means thatyou need to be dialted every 6 months" I replied, no. I don't need to be dilated because I don't have macular degeneration. Macular degeneration and lupus" Lupus Community.. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. The Risk of Retinal Toxicity with Plaquenil. Hydroxychloroquine maculopathy shares characteristic with several acquired or congenital diseases of the macula. The differential diagnosis includes age-related macular degeneration, cone dystrophy, rod and cone dystrophy, Stargardt’s disease, neuronal ceroid lipofuscinosis, and fenestrated sheen macular dystophy. Management General treatment While Plaquenil can cause toxicity damage to the macula, it will not cause a macular pucker. If you are on Plaquenil, it is recommended that you have your retina checked regularly by an ophthalmologist, including imaging studies, which can help find damage to the macula. Sep 15, 2014 Fundus autofluorescence FAF indicates marked changes of macular toxicity in the mild and severe cases, represented by the central mottled hypo autofluorescence with surrounding rim of hyper autofluorescence, due to the retinal pigment epithelium RPE loss. FAF is a sensitive indicator of the RPE degeneration caused by the toxic progression.