Friends and family help but they really just dont get it! Anyways- been diagnosed and have been taking plaquenil since around October- it was helping but my wrists and fingers were still in so much pain that I couldn't even get dressed in the mornings! So I was taking dose packs to help w the pain and my rheumatology finally put me on prednisone- TERRIBLE. I couldnt sleep at night, had awful night sweats, weight gain...it. Plaquenil pregnancy safety Plaquenil and cholesterol Plaquenil and oral pigmentation Are there special precautions those living with rheumatoid arthritis RA should take around the coronavirus COVID-19, given a compromised immune system? Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in. For patients with a disease duration less than 6 months, clinical practice guidelines recommend use of combination DMARDs such as sulfasalazine plus hydroxychloroquine for those with moderate disease activity and poor prognostic features and is an option for those with high disease activity and poor prognostic features. So my doctor wanted to put me on methotrexate and I read sooo many terrible things about it that I begged her to let me try something else first before going to the extreme w the methotrexate. Being a 23 yr old female who is getting married in July- weight gain feels like the worst thing that could happen to you. Plaquenil and sulfasalazine combination Sulfasalazine and Plaquenil drug interactions - eHealthMe, Plaquenil Oral Interactions with Other Medication What does plaquenil do for sjogrens If the plaquenil is helping and they say you need it, I'd take it - the side effects will go away. I've not had experience with sulfasalazine - but from what I've read, the side effects of that med are about the same as those of plaquenil. BTW - sulfasalazine is an anti-inflammatory. Plaquenil and sulfasalazine - Autoimmune Disorders - MedHelp. Plaquenil hydroxychloroquine sulfate dose, indications.. Methotrexate vs Sulfasalazine Comparison -. Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine, or a combination of the three medications Results of a two‐year, randomized, double‐blind, placebo‐controlled trial Summary Drug interactions are reported among people who take Hydroxychloroquine sulfate and Sulfasalazine together. This study is created by eHealthMe based on reports of 1,913 people who take Hydroxychloroquine sulfate and Sulfasalazine from Food and Drug Administration FDA, and is updated regularly. Mar 27, 2012 Its efficacy is similar to that of methotrexate, but the choice of sulfasalazine may be made if the patient is a heavy drinker, or may become pregnant. It is sometimes prescribed by itself or maybe prescribed in combination with hydroxychloroquine Plaquenil or with methotrexate, it usually takes 6-12 weeks to start to feel the benefits.