It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Can u stop taking plaquenil Hydroxychloroquine liver toxicity Plaquenil can produce pigment changes in the macula of the retina. The retina is the part of the back of the eye that you see with. The macula is the central part of the retina responsible for central fine vision. With Plaquenil related toxicity, the pigment in the macula can change and alter vision by producing blurring and distortion of objects. Sep 15, 2014 Retinal Screening for Hydroxychloroquine Plaquenil Toxicity Medications used to treat various systemic conditions can have ocular side effects. In particular, chloroquine and hydroxychloroquine Plaquenil are two such medications, with the potential for retinal toxicity. Retinal detachment is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years, also take medication Concerta, and have Joint deposit For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation and scaling, skin rash, vertigo, weight loss, and occasionally urinary incontinence. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. Plaquenil retinal deposits Optometric Management - Retina, Retinal Screening for Hydroxychloroquine Plaquenil Toxicity. Is hydroxychloroquine the same as plaquenilCan you get chloroquine over the counter Symptoms and SignsMechanism of ToxicityMedication DosageRisk For ToxicityMonitoring GuidelinesConclusion Hydroxychloroquine-Induced Retinal Toxicity -. Will you have Retinal detachment with Plaquenil -. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Rarely plaquenil can have toxic effects on the retina. If the daily dose of plaquenil exceeds the body's ability to clear out the medication then it can leave deposits in different tissues of the body, particularly the underlay beneath the central vision part of the retina macula. Sep 13, 2019 Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Deficiency Of Granulocytes A Type Of White Blood Cell.