It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Sle on plaquenil Hydroxychloroquine scleroderma Chloroquine clinical trials glioma Chloroquine take how long to work Hydroxychloroquine is one of several antimalarial drugs that have anti-inflammatory effects useful in other diseases. It is licensed in the UK for the treatment of malaria. Hydroxychloroquine is particularly effective for systemic lupus erythematosus SLE and discoid lupus erythematosus DLE. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells anemia. Sep 13, 2019 Applies to hydroxychloroquine compounding powder, oral tablet. Cardiovascular. Frequency not reported Cardiomyopathy can result in fatal cardiac failure, biventricular hypertrophy. Dermatologic-Pigmentary changes in skin and mucous membranes, bleaching of hair, and alopecia are usually reversible when therapy is discontinued. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Hydroxychloroquine skin lightening Hydroxychloroquine DermNet NZ, Hydroxychloroquine Plaquenil Side Effects & Dosage for. Can plaquenil cause acneWhat happens when you drink red wine on hydroxychloroquinePlaquenil and raynaud& 39 Plaquenil or hydroxychloroquine has been known to cause a darkened discoloration of skin and/or mucous membranes. This is considered an adverse reaction and should be discussed with your prescriber. It is important to evaluate this color change to make sure there is nothing else wrong. Skin Discoloration and Plaquenil - Arthritis Information. Plaquenil Side Effects Common, Severe, Long Term -. Hydroxychloroquine Plaquenil. Hydroxychloroquine HCQ-associated hyperpigmentation is uncommon, with onset ranging from 3 months to 22 years following the initiation of therapy 1. A 32-year-old woman presented with a 1.5-year history of symmetric polyarthritis, positive rheumatoid factor, and anticyclic citrullinated peptide antibody, without erosive joint changes. Hydroquinone is used to lighten the dark patches of skin also called hyperpigmentation, melasma, " liver spots," "age spots," freckles caused by pregnancy, birth control pills, hormone medicine. Hydroxychloroquine Plaquenil stimulates the pigment producing cells in the skin called melanocytes. As a result, there is both hemosiderin iron and melanin accumulation in the dermis. The exact reasons why this phenomenon happens is not clear.