Additionally, another exception occurred while executing the custom error page for the first exception. Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. Plaquenil help migraine Chloroquine resistant malaria vivax How effective is plaquenil for scarring alopecia Chloroquine dose for child Peripheral retina was unremarkable OU. Fundus photos, visual field 10-2 were ordered as well as a spectral domain ocular coherence tomography SD-OCT see Figures 1-3. The appearance of disruption of the photoreceptor integrity line, perifoveal thinning, and paracentral scotomas confirmed a high likelihood of toxicity in this patient. Although the incidence of macular toxicity is infrequent with Plaquenil use at a dosage of 200mg or 400mg q.d. its visual impact can be devastating. 2,3. The associated classic retinal toxicity is described as a bull’s eye maculopathy ring of depigmented retinal pigment epithelium that spares the foveal area. Baseline screening and annual screening after five years is recommended. Ancillary testing modalities, such as SD-OCT, mfERG, and autofluorescence provide sensitive screening tools that complement the 10-2 HVF in detection of early hydroxychloroquine toxicity. Full clinical history and course And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. Plaquenil toxicity 10-2 Dr. Noskow's Case Report Plaquenil Toxicity - Hollywood., New Plaquenil Guidelines Can plaquenil help osteoarthritisDoes plaquenil come as an injectionPlaquenil and skin changes The main outcomes were toxicity as determined by characteristic visual field loss or retinal thinning and photoreceptor damage. They also examined risk factors and prevalence. The study findings revealed that when hydroxychloroquine was used at doses 5mg /kg, the risk of retinopathy was 1% in the first 5 yrs. 2% in 10 yrs. 20 % after 20 yrs. My Take on New Ocular Screening Guidelines for Plaquenil.. Hydroxychloroquine Plaquenil Toxicity and.. How to Succeed in Plaquenil Screenings. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. The 10-2 red test has been recommended in the past as the testing strategy of choice for HCQ toxicity due to its sensitivity. 1,5 Easterbrook 1 reported the 10-2 red test to be 91% sensitive for detection of HCQ toxicity. However, he also reported a low specificity of 57% for this test. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.