Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Plaquenil guidelines review of optometry Biaxin and plaquenil for lyme Hydroxychloroquine 200 mg tab generic plaquenil Find patient medical information for Chloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Chloroquine side effects Get emergency medical help if you have signs of an allergic reaction hives, difficult breathing, swelling in your face or throat or a severe skin reaction fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling. Chloroquine CQ is used to prevent and treat malaria and amebiasis, while hydroxychloroquine HCQ, a less toxic metabolite of chloroquine, is used to treat rheumatic diseases such as systemic lupus erythematosus SLE, rheumatoid arthritis RA, juvenile idiopathic arthritis JIA and Sjogren's syndrome. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine toxicity symptoms Chloroquine toxicity -, Chloroquine Uses, Side Effects & Warnings - Chloroquine high creatinineQue es el plaquenilHow to wean from plaquenil Chloroquine may cause a condition that affects the heart rhythm QT prolongation. QT prolongation can rarely cause serious rarely fatal fast/irregular heartbeat and other symptoms such as. Chloroquine Oral Uses, Side Effects, Interactions.. Chloroquine And Hydroxychloroquine Toxicity - StatPearls - NCBI Bookshelf. Symptom combinations for Chloroquine toxicity.. Get emergency help immediately if any of the following symptoms of overdose occur Symptoms of overdose. Cold, clammy skin decreased urine drowsiness dry mouth fast, weak pulse increased thirst lightheadedness, dizziness, or fainting loss of appetite muscle pain or cramps numbness or tingling in the hands, feet, or lips As we know FQ’s exhibit cumulative toxicity. From the article I referenced above we know that Chloroquine is a chemical cousin to the FQ’s so it is entirely plausible that Chloroquine would contribute to the cumulative toxicity. Both drugs are known to be toxic to the mitochondria 3,4. Chloroquine and hydroxychloroquine belong to the quinolone family. They are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity, although their therapeutic and toxic doses differ.