It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Ra plaquenil Hydroxychloroquine patient reviews Long term ratings 3/5. This is a reivew of how effective Plaquenil hydroxychloroquine sulfate is for Osteoarthritis and for what kind of people. The study is created by eHealthMe from 10 Plaquenil users and is updated continuously. On eHealthMe, you can evaluate side effects and drug interactions from 16 million FDA reports. Feb 19, 2020 SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Screening requires the use of tests, such as 10–2 visual fields and SD-OCT and other modern techniques, such as autofluorescence imaging and multifocal electroretinography, to demonstrate early retinal damage.” 1 Melles & Marmor. The Risk of Toxic Retinopathy in Patients on Long-term Hydroxychloroquine Therapy. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Is long term use of plaquenil safe Hydroxychloroquine Plaquenil, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Plaquenil guidelines 2019Hydroxychloroquine sulfate side effects rheumatoid arthritis Feb 19, 2020 Long-term studies in animals have not been conducted to evaluate the carcinogenic potential of PLAQUENIL. The mutagenic potential of hydroxychloroquine was not evaluated. However, chloroquine has been shown to be a catalytic inhibitor of DNA repair enzymes topoisomerase II and to produce weak genotoxic effects through this mode of action. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Plaquenil Risk Calculators. Continuation of long term treatment with hydroxychloroquine.. Jul 17, 2017 At least two of the concerns you mention, weight gain and osteoporosis, are common side effects of long-term prednisone use. If you are pregnant or considering becoming pregnant, discuss Plaquenil with your doctors. Though Plaquenil is generally regarded as safe during pregnancy, it is recommended that effective birth control is used throughout the course of Plaquenil treatment and for up to six months after treatment is stopped. Serious Side Effects of Plaquenil. If you are taking Plaquenil long-term, such as for an autoimmune condition, your doctor should regularly check you for potential serious side effects.