In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Fundus in chloroquine Common side effects of plaquenil Plaquenil make me itch Plaquenil platelets Lithium aggravates psoriasis in about half of those with psoriasis who take it. Antimalarials Plaquenil, Quinacrine, chloroquine and hydroxychloroquine may cause a flare of psoriasis, usually two to three weeks after the drug is taken. Hydroxychloroquine is the least likely to cause side effects. Rheumatoid arthritis RA, the most common form of inflammatory arthritis, can lead to significant pain, disability, and deformity, and is a multisystem autoimmune disorder. The hallmark of this disease, erosive joint destruction, results from unchecked synovial inflammation, which can damage articular cartilage and bone, with resultant loss of joint function. Otezla is an oral systemic and phosphodiesterase 4 PDE4 inhibitor. PDE4 inhibitors suppress characteristic features in the immune response, such as cell recruitment and activation of inflammatory cells. 8,9 As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Otezla and plaquenil Two things - sleep with PsA, and Otezla? PsoriaticArthritis, Perioperative Management of Medications Used in the. What is chloroquine chemoprophylaxisChloroquin quinineDesethyl hydroxychloroquine Hydroxychloroquine Plaquenil® is an antibiotic used to treat malaria, but it also works to treat symptoms of RA, lupus, and other rheumatic diseases. It can reduce your joint pain and swelling. In the long term, it may help prevent joint damage or lower your risk of joint disability. DMARDs Disease-Modifying Antirheumatic Drugs – CreakyJoints. What Types of Medications are Used to Treat Psoriatic Arthritis?. Plaquenil Oral Interactions with Other Medication. Approved Uses. Otezla® apremilast is a prescription medicine approved for the treatment of patients with moderate to severe plaque psoriasis for whom phototherapy or systemic therapy is appropriate. Otezla is a prescription medicine approved for the treatment of adult patients with active psoriatic arthritis. I've had osteoarthritis since about 20yrs old I'm 43 in my neck first, then moved down my back and into my hips throughout my 20's. So badly so, that in my early thirties I had to stop working. My back would lock up and swell so badly that it hurt to breathe. During pregnancy, Otezla should be used only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding. Additional Information. Our Otezla apremilast Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.