Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Interactions with plaquenil and fluconazole Plaquenil causing depression Retinal pigment epithelial mottling of macula plaquenil Headache pain in head 175 people, 29.51% ; Back Pain 173 people, 29.17% ; Fatigue feeling of tiredness 166 people, 27.99% ; Nausea feeling of having an urge to vomit 148 people, 24.96% ; Most common conditions people have * Pain 47 people, 7.93% ; Osteoporosis bones weak and more likely to break 34 people, 5.73% What Is Plaquenil? Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Call your doctor at once if you have headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats; very slow heart rate, weak. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil back pain and headache Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Side Effects of Plaquenil Hydroxychloroquine, Malarone for chloroquine resistance ncbiDoes plaquenil reduce painVd chloroquineHydroxychloroquine widely useChloroquine paludisme Neck pain and headache pain can cause a dull nagging, persistent pain in your neck or head. Depending on the cervical nerves affected, you may experience sharp shooting pains at the back of your skull, temple, or behind one eye. This type of headache pain can feel as if someone is stabbing you. Neck Pain and Headaches - Could Your Neck Pain Cause a Headache?. Plaquenil Uses, Dosage & Side Effects -. Plaquenil Side Effects Common, Severe, Long Term -. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. When I started Plaquenil back in November last year, I had terrible headaches which started about 1/2 an hour after taking pills. It happened so consistently that I started taking tylenol when I would take it. I would lay down with an ice pack under my neck and darken the room. My eyes have been terribly un-focused and I have been in pain for most of that time. I was put on Imuran during this time, which I felt did nothing to stop the pain of R. A. A I was thinking Plaquenil was not helping with my symptoms, but I was so wrong! We have just received a shipment of it here and I started back on it.