Chloroquine used where

Discussion in 'International Pharmacy' started by marian, 10-Mar-2020.

  1. Romelyus New Member

    Chloroquine used where


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

    Hydroxychloroquine method of action Plaquenil and cns Plaquenil dizziness

    Chloroquine resistance is widespread and, at present, is particularly prominent in various parts of the world including sub- Saharan Africa, Southeast Asia, the Indian subcontinent, and over large portions of South America, including the Amazon basin 1. Mar 17, 2019 Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Is chloroquine a cure for coronavirus? Some scientists are touting the efficacy of the drug in preliminary studies, but are also noting that much more research needs to be done before confirming.

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Chloroquine used where

    Chloroquine Uses, Side Effects & Warnings -, Hydroxychloroquine Uses, Dosage & Side Effects -

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  4. Since Chloroquine phosphate tablets are known to concentrate in the liver, it should be used with caution in patients with hepatic disease or alcoholism or in conjunction with known hepatotoxic drugs.

    • Chloroquine - FDA prescribing information, side effects..
    • Is Chloroquine a Cure for Coronavirus? Scientists Say..
    • Chloroquine Oral Route Proper Use - Mayo Clinic.

    Because chloroquine active only against asexual erythrocytic forms of Plasmodium not exoerythrocytic stages, 14-day regimen of primaquine indicated to eradicate hypnozoites and prevent delayed primary attacks or relapse and provide a radical cure whenever chloroquine used for treatment of P. ovale or P. vivax malaria. 134 143 Chloroquine phosphate is in a class of drugs called antimalarials and amebicides. It is used to prevent and treat malaria. It is also used to treat amebiasis. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Chloroquine. Research by German scientists to discover a substitute for quinine led to the synthesis in 1934 of Resochin chloroquine and Sontochin 3-methyl-chloroquine. These compounds belonged to a new class of antimalarials, the four-amino quinolines. The German research went no further and the formula for Resochin was passed to a US.

     
  5. uncle Buddah Moderator

    I am trying to find out if anyone's had luck with plaquenil for joint pain? How Does Plaquenil Work For Rheumatoid Arthritis Taking Plaquenil for Rheumatoid Arthritis Joint Pain and Plaquenil Sjogrens - reddit
     
  6. mebru Guest

    La dieta es un aspecto esencial de la vida, tengamos o no una enfermedad crónica. Empezando por la pregunta que todos nos hacemos: No. Así de claro nos lo dicen en la Fundación Americana de Lupus. Todos los dietistas y nutricionistas nos recomiendan repartir las comidas en 5 tomas. Cada vez que ingreso en el hospi las enfermeras me dan un papelito donde lo pone bien claro, je :p. A mí, por ejemplo, me sienta mal la leche entera, así que tomo semi y sin lactosa 😉 . Sólo para los que toman anticoagulantes como el sintrom o la warfarina, que actúan sobre la vitamina K. Que puedo tomar para engordar ? Yahoo Respuestas Hidroxicloroquina Plaquenil Qué comer cuando el hipotiroidismo te hace subir de peso
     
  7. apol Well-Known Member

    Dissecting pharmacological effects of chloroquine in cancer. Chloroquine Fusion with Lysosome P62-substrate Targeting to autophagosome Targeting for degradation Misfolded proteins Cell death signaling proteins Cell survival signaling proteins Cell survival Cell survival Cell death Cell survival Cell death Cell death Result of complete process Failure Figure 1.

    CST - Chloroquine - Cell Signaling Technology