Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Hydroxychloroquine-mediated retinopathy Plaquenil toxicity 10-2 Feb 20, 2013 Most, if not all of the chloroquine available for aquarium use is in the form of chloroquine diphosphate as opposed to chloroquine hydrochloride or sulfate. This means that dosing an aquarium with this drug will also add some phosphate PO 4 to the water when the compound dissociates as it dissolves. Chloroquine is an established antimalarial agent that has been recently tested in clinical trials for its anticancer activity. The favorable effect of chloroquine appears to be due to its ability to sensitize cancerous cells to chemotherapy, radiation therapy, and induce apoptosis. Nausea, vomiting, and diarrhoea are common side effects, but are usually transient or resolve on the reduction of the dose. They can be minimised by taking the hydroxychloroquine with food. Cutaneous effects The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine diphosphate side effects Chloroquine Phosphate chloroquine phosphate dose., Chloroquine Is a Zinc Ionophore - PubMed Central PMC Hidroxicloroquina plaquenil org Chloroquine Phosphate. Uses. Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter. Side Effects. Precautions. Interactions. Chloroquine Oral Uses, Side Effects, Interactions.. Hydroxychloroquine DermNet NZ. CHLOROQUINE Drug BNF content published by NICE. Arrhythmogenic drugs There may be an increased risk of inducing ventricular arrhythmias if chloroquine is used concomitantly with other arrhythmogenic drugs, such as amiodarone or moxifloxacin. Ampicillin In a study of healthy volunteers, chloroquine significantly reduced the bioavailability of ampicillin. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away Belly pain. Stomach cramps. Not hungry. Upset stomach or throwing up. Headache. Diarrhea. Change in color of skin. Change in color of hair. Hair loss. These are not all of the side effects that may occur. Chloroquine diphosphate CQ is a hydrophilic drug with low entrapment efficiency in hydrophobic nanoparticles NP. Herpes simplex virus type 1 HSV-1 is an enveloped double-stranded DNA virus.