Additionally, another exception occurred while executing the custom error page for the first exception. Plaquenil, hydroxychloroquine (HCQ), is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and other inflammatory and autoimmune diseases. Chloroquine breast cancer Plaquenil side effects skin Hydroxychloroquine used for hair loss Plaquenil for lupus mechanism Aug 30, 2011 Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. A 26-year-old black female presented in office for her annual comprehensive eye exam. Her medical history was significant for Plaquenil therapy spanning 12 years with a daily dose of 200mg twice daily. She presented with a best-corrected visual acuity of 20/20 OD and 20/20 OS. All preliminary testing revealed normal findings. Remember, any patient who is at a high risk for Plaquenil toxicity should be examined on an annual basis following the baseline exam. The goal of monitoring/screening is to identify early macular damage prior to irreversible vision loss or even before visible signs of bull’s eye maculopathy. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Eye exams for plaquenil Eye screening for patients taking hydroxychloroquine Plaquenil, How to Succeed in Plaquenil Screenings Is plaquenil porcine based Multifocal Electroretinopathy measures electrical responses of various cell types in the retina. It is thought that although the bull’s eye seen on ophthalmic exam represents a disruption of the pigmented part of the retina, it is the photoreceptors that are the targets of hydroxychloroquine toxicity. My Take on New Ocular Screening Guidelines for Plaquenil RheumNow.. New Plaquenil Guidelines. Starting Plaquenil BEFORE Eye Exam? - Scleroderma - Inspire. If you take Plaquenil and have had any changes in your vision, its important to notify your ophthalmologist or optometrist as soon as possible. If you take this medication, it is important to have annual eye exams by your ophthalmologist, so he/she can monitor changes within your eye. Aug 01, 2009 i have only been taking plaquenil for 18 mths and recently found out that i have macula degeneration, my last eye exam was only 6 mths ago and there was no sign of anything then. i strongly advise 6 monthly eye exams and if there is the slightest blurring of vision get it checked out. Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so.